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Explore Our Research Groups
Stress and Immunity, Laboratory of Translational Research
Location: LMU Klinikum Großhadern, Munich, Germany
Focus: Effects of microgravity, psychological and physical stress on the immune system at a cellular and systemic level.
Group Leader: Prof. Dr. Alexander Chouker
Group Members:
Major Projects:
Major Publications:
Vascular Aging and Brain Health laboratory
Location: University of Waterloo, Waterloo, Ontario, Canada
Focus: Vascular health in astronauts; Effects of vascular aging on brain blood flow
Group Leader: Prof. Richard Hughson
Group Members:
Dr. Andrew Robertson, Research Assistant Professor
Dr. Danielle Greaves, Space Research Manager
Dr. Carmelo Mastrandrea, Postdoctoral Fellow
Dr. Roxy Fournier, Postdoctoral Fellow
Dr. Eric Hedge, Postdoctoral Fellow
Dr. Jeremy Rabineau, Postdoctoral Fellow
Carol Bryans, Master Student
Major Projects: Prof. Richard Hughson is Principal Investigator of 6 projects on the International Space Station. The laboratory is also involved in numerous head-down bed rest and parabolic flights projects. Besides this, thanks to its location in a long-term care and retirement village, studies are also conducted on older adults.
Major Publications:
• Hughson RL, Robertson AD, Arbeille P, Shoemaker JK, Rush JWE, Fraser KS, Greaves DK. (2016). Increased post-flight carotid artery stiffness and inflight insulin resistance resulting from six-months spaceflight in male and female astronauts. American Journal of Physiology: Heart and Circulatory Physiology. 310: H628-H638.
• Fitzgibbon-Collins, L. K., Noguchi, M., Heckman, G. A., Hughson, R. L., & Robertson, A. D. (2019). Acute reduction in cerebral blood velocity on supine-to-stand transition increases postural instability in young adults. American Journal of Physiology-Heart and Circulatory Physiology, 317(6), H1342-H1353.
• Hedge, Eric T., Carmelo J. Mastrandrea, and Richard L. Hughson. “Loss of cardiorespiratory fitness and its recovery following two weeks of head-down bed rest and the protective effects of exercise in 55-to 65-yr-old adults.” Journal of Applied Physiology 134.4 (2023): 1022-1031.
• Mastrandrea, C. J., Hedge, E. T., Robertson, A. D., Heckman, G. A., Ho, J., Granados Unger, F., & Hughson, R. L. (2023). High-intensity exercise does not protect against orthostatic intolerance following bedrest in 55-to 65-yr-old men and women. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 325(2), R107-R119.
• Mastrandrea, C. J., Greaves, D. K., Shoemaker, J. K., Blaber, A. P., Arbeille, P., & Hughson, R. L. (2024). Lower body negative pressure identifies altered central vein characteristics without accompanying changes to baroreflexes in astronauts within hours of landing. Scientific Reports, 14(1), 1215.
Explore Our Research Groups
Stress and Immunity, Laboratory of Translational Research
Location: LMU Klinikum Großhadern, Munich, Germany
Focus: Effects of microgravity, psychological and physical stress on the immune system at a cellular and systemic level.
Group Leader: Prof. Dr. Alexander Chouker
Group Members:
Major Projects:
Major Publications:
Vascular Aging and Brain Health laboratory
Location: University of Waterloo, Waterloo, Ontario, Canada
Focus: Vascular health in astronauts; Effects of vascular aging on brain blood flow
Group Leader: Prof. Richard Hughson
Group Members:
Dr. Andrew Robertson, Research Assistant Professor
Dr. Danielle Greaves, Space Research Manager
Dr. Carmelo Mastrandrea, Postdoctoral Fellow
Dr. Roxy Fournier, Postdoctoral Fellow
Dr. Eric Hedge, Postdoctoral Fellow
Dr. Jeremy Rabineau, Postdoctoral Fellow
Carol Bryans, Master Student
Major Projects: Prof. Richard Hughson is Principal Investigator of 6 projects on the International Space Station. The laboratory is also involved in numerous head-down bed rest and parabolic flights projects. Besides this, thanks to its location in a long-term care and retirement village, studies are also conducted on older adults.
Major Publications:
• Hughson RL, Robertson AD, Arbeille P, Shoemaker JK, Rush JWE, Fraser KS, Greaves DK. (2016). Increased post-flight carotid artery stiffness and inflight insulin resistance resulting from six-months spaceflight in male and female astronauts. American Journal of Physiology: Heart and Circulatory Physiology. 310: H628-H638.
• Fitzgibbon-Collins, L. K., Noguchi, M., Heckman, G. A., Hughson, R. L., & Robertson, A. D. (2019). Acute reduction in cerebral blood velocity on supine-to-stand transition increases postural instability in young adults. American Journal of Physiology-Heart and Circulatory Physiology, 317(6), H1342-H1353.
• Hedge, Eric T., Carmelo J. Mastrandrea, and Richard L. Hughson. “Loss of cardiorespiratory fitness and its recovery following two weeks of head-down bed rest and the protective effects of exercise in 55-to 65-yr-old adults.” Journal of Applied Physiology 134.4 (2023): 1022-1031.
• Mastrandrea, C. J., Hedge, E. T., Robertson, A. D., Heckman, G. A., Ho, J., Granados Unger, F., & Hughson, R. L. (2023). High-intensity exercise does not protect against orthostatic intolerance following bedrest in 55-to 65-yr-old men and women. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 325(2), R107-R119.
• Mastrandrea, C. J., Greaves, D. K., Shoemaker, J. K., Blaber, A. P., Arbeille, P., & Hughson, R. L. (2024). Lower body negative pressure identifies altered central vein characteristics without accompanying changes to baroreflexes in astronauts within hours of landing. Scientific Reports, 14(1), 1215.